Dutasteride vs Finasteride: Which Hair Loss Medication Works Better?
If you’re researching medications for hair loss, you’ve likely heard of Finasteride. But what about Dutasteride?
Both are oral medications that block the hormone DHT—a leading cause of hair follicle miniaturisation in male pattern baldness. While Finasteride is more widely prescribed, Dutasteride is often more effective—and it’s the option we recommend more often at The Derm Lab.
Here’s why.
💊 What Is Finasteride?
Finasteride (brand name: Propecia) works by inhibiting Type II 5-alpha reductase, the enzyme responsible for converting testosterone to dihydrotestosterone (DHT)—the hormone that causes hair follicles to shrink.
- Approved for male pattern hair loss
- Taken orally once a day
- Reduces scalp DHT by ~60–70%
- Slows or halts shedding, especially in the crown area
💊 What Is Dutasteride?
Dutasteride (brand name: Avodart) is a more potent DHT blocker. It inhibits both Type I and Type II 5-alpha reductase, making it more comprehensive in its DHT suppression.
- Not officially TGA-approved for hair loss (but prescribed off-label by many clinics)
- Reduces scalp DHT by ~90%
- Often used when Finasteride results plateau
- Longer half-life (~5 weeks vs. 6 hours for Finasteride)
🧪 Dutasteride vs Finasteride: Comparison Table
| Feature | Finasteride | Dutasteride |
|---|---|---|
| DHT reduction | ~60–70% | ~90% |
| 5α-reductase inhibition | Type II only | Type I + Type II |
| Onset of results | 3–6 months | 3–6 months |
| Half-life | ~6 hours | ~5 weeks |
| Clinical approval (hair loss) | ✅ Yes | ⚠️ Off-label (used widely) |
| Dosage | 1 mg daily | 0.5 mg daily |
💡 Why We Prefer Dutasteride at The Derm Lab
While both medications are effective, we often recommend Dutasteride for men who:
- Have more advanced hair loss
- Haven’t responded well to Finasteride
- Want a stronger, longer-lasting DHT blockade
- Are undergoing hair transplant surgery and want optimal long-term results
Many of our clients who switch to Dutasteride report stronger hair retention and improved regrowth after 3–6 months.
⚠️ What About Side Effects?
Both medications can carry side effects, including:
- Reduced libido
- Erectile dysfunction
- Decreased semen volume
These occur in a small percentage of men and are typically dose-dependent.
At The Derm Lab, we provide thorough medical screening and support to find the safest, most effective plan for each individual.
📍 Book a Hair Loss Consultation in Melbourne
Our team specialises in evidence-based medical and surgical hair restoration. Whether you’re considering oral medications, PRP, or a transplant—we’ll help you decide what’s right for you.
👉 Book a confidential consultation at The Derm Lab and take control of your hair loss with expert guidance.
As always, proper consultation with your doctor is required. The information provided above is for educational purposes only.
